|
KMID : 0364219900330030297
|
|
Korean Journal of Zoology
1990 Volume.33 No. 3 p.297 ~ p.302
|
|
|
Effects of Ginseng Saponin on Serum Alanine Aminotransferase Activity in Trained Rats
|
|
Kim Hee-Kyung
Nam Sang-Yul
|
|
|
Abstract
|
|
|
|
The effects of ginseng saponin on the activity of serum alanine aminoiransferase (ALT) in trained rats were examined. The trained group was given a chronic swimming bout (approx. 90 min/day) for 50 days, and ginseng group was given an oral administration of ginseng saponin (150mg/kg/day) for 2 weeks. Ginseng treated-trained group was given an oral administration of ginseng saponin for 2 weeks prior to the termination of a swimming bout. In this experiment, male rats of Sprague-Dawley strain (250 ± 20 g) were used. The activities of serum ALT in trained and in ginseng groups increased 72.89% (P < 0.01) and 57.14% (P < 0.01) than in control groups, respectively. Also, the activities of serum ALT increased 69.66% (P <0.01) in saline treated-trained group, and 79.31% (P < 0.01) in ginseng treated-trained group than in control groups which were given saline solution and kept sedentary. The effect of ginseng saponin, as revealed by comparing the ginseng treated-trained group with the saline treated-trained group, was not significant. The present study suggests that training and ginseng saponin significantly increased the activity of serum ALT in rats, but that, in ginseng treated-trained group, ginseng saponin did not raise any further the increased activity of serum ALT by training.
|
|
|
KEYWORD
|
|
|
Gisneg saponin , Alanine amiotransferase
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|